Find the gaps in evidence synthesis
Describe a clinical area. SynthGap searches the published literature, checks each candidate against existing systematic reviews, and proposes novel meta-analysis topics — with the primary studies to back them.
Sign up free: no card needed. Every plan comes with usage that renews every month.
The agent searches the literature for high-impact, relevant primary studies. It then checks which of them are cited and what systematic reviews and meta-analyses have already been done, and comes up with the best topic, with its estimated PICO and the studies it estimates the topic would include.
Pick the plan that fits how you work
Start free, no card needed. Every plan comes with usage that renews every month.
Free
For a first look
$0
No card needed. Usage resets every month.
Limited use
- Discovery runs
- The interactive literature map
- Chat about your results
Plus
For finding and checking topics
$10/monthSave 20%
Billed $30 every 3 months. Usage resets every month.
Standard usage
Everything in Free, plus
- Deep analysis: the topic refined, its studies, a critical report and a verdict
- Reserve a topic and draft a PROSPERO entry
- Top up when you run low
Pro
For scanning a whole field
$24/monthSave 20%
Billed $72 every 3 months. Usage resets every month.
More than 3x the usage of Plus
Everything in Plus, plus
- SweepsExplore a whole research area in one go: Agents do a broad survey of the topic and come up with most of the high impact available topics and every topic found comes back ranked. You choose which to analyse. A sweep takes 80 to 120 minutes, and chat stays open while it runs.
- A preview of what a meta-analysis on each topic would look likeEffect size calculationPooled ratios or mean differences, each with a confidence intervalHeterogeneity assessmentI², τ², Cochran's Q and a prediction intervalGraphsForest plot, funnel plot and more
Need more? You can top up by paying for credits, in any amount.
Already on Plus? Moving to Pro costs only the difference: $17.50 if you pay every month, $42 if you pay every 3 months.
Prices are in US dollars. A plan renews automatically until you cancel, which you can do any time yourself from Settings in the account menu after signing in. See the Refund & Cancellation Policy.